Failing Epidural Analgesia During Labor

This prospective multicenter observational study is being conducted at the Gregorio Marañón University General Hospital and the La Paz University Hospital in Madrid, Spain. The recruitment period began on January 12, 2026, and will continue until February 12, 2027. Patients over 18 years of age requesting epidural analgesia for labor are included. Exclusion criteria are: age under 18; stillbirth; continuous spinal anesthesia; refusal to participate in the study. The primary objective of the study is to calculate the incidence of epidural analgesia failure during labor. Secondary objectives are: identification of potential risk factors for epidural analgesia failure; failure of epidural anesthesia for emergency cesarean birth; maternal postpartum recovery at 24 and 48 hours using the Spanish-validated version of ObsQoR-10 questionnaire.

NCT Number	NCT07473609
Lead Sponsor	Nicolas Brogly
Conditions	Failed Epidural Analgesia, Post-partum Recovery
Enrollment	500 participants
Start Date	2026-01-12
Primary Completion	2026-07-12 (estimated)
Study Completion	2027-02-12 (estimated)
Updated on ClinicalTrials.gov	2026-03-16