Clinical Trial

Thyroid Carcinoma in Cancer Patients Undergoing Radiotherapy

Recruiting
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Record status
This record was last updated March 16, 2026 (before its estimated July 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study aims to define the optimal surveillance strategy for children exposed to radiotherapy by assessing the incidence, risk factors, and timing of thyroid nodules and differentiated thyroid cancer. It also investigates the genetic features of thyroid tumors in this population to identify predictive biomarkers of onset, malignancy, and aggressiveness. Ultimately, the goal is to support more personalized management, including tailored surgery and targeted therapies.
Trial Details
NCT Number NCT07473518
Lead Sponsor IRCCS Azienda Ospedaliero-Universitaria di Bologna
Conditions Thyroid Carcinoma, Pediatric Cancer
Enrollment 2,550 participants
Start Date 2025-07-30
Primary Completion 2026-07-30 (estimated)
Study Completion 2027-07-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-16