Clipless Versus Conventional Laparoscopic Cholecystectomy Using Harmonic Scalpel

This randomized controlled trial compares the operative outcomes of clipless laparoscopic cholecystectomy using a harmonic scalpel (HS) versus conventional clip-based laparoscopic cholecystectomy (CLC) in patients with gallstone disease. The primary goals are to determine if the clipless HS technique reduces operative time and intraoperative blood loss. Secondary outcomes include the length of postoperative hospital stay and the rate of port-site infections.

NCT Number	NCT07473388
Lead Sponsor	Services Hospital, Lahore Collaborators: Services Institute of Medical Sciences, Pakistan
Conditions	Cholecystectomy, Laparoscopic, Cholecystitis, Gall Stones (& [Calculus - Gall Bladder])
Enrollment	158 participants
Start Date	2020-02-01
Primary Completion	2025-06-15 (estimated)
Study Completion	2025-12-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-16