Diagnostic Accuracy of Clinical Tests and Diagnostic Criteria for Piriformis Syndrome

Piriformis syndrome is a clinical condition characterized by buttock pain and/or sciatic-like symptoms, and its diagnosis remains challenging because there is no universally accepted diagnostic standard. This study aims to evaluate the diagnostic accuracy of commonly used diagnostic criteria and clinical tests for piriformis syndrome. Participants with suspected piriformis syndrome will undergo standardized physical examination and assessment of predefined diagnostic criteria. Ultrasound-guided injection of 5 mL of 2% lidocaine into the piriformis muscle will be used as the reference diagnostic procedure. A reduction of 50% or more in pain after injection will be considered confirmation of piriformis syndrome. The diagnostic performance of clinical tests and diagnostic criteria will be analyzed accordingly.

NCT Number	NCT07473349
Lead Sponsor	Istanbul University - Cerrahpasa
Conditions	Piriformis Syndrome, Gluteal Pain
Enrollment	75 participants
Start Date	2026-03-15
Primary Completion	2026-09-15 (estimated)
Study Completion	2026-09-15 (estimated)
Updated on ClinicalTrials.gov	2026-03-17