Clinical Trial

MULTIMODAL APPROACH IN THE DIAGNOSIS OF SEPTIC AKI

Study acronym: SEPTIC AKI
Not Yet Recruiting
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Record status
This record was last updated March 16, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
In recent studies, it has been reported that the renal resistance index is effective in detecting sepsis-related acute renal failure (SA-AKI) in the early period. Similarly, urinary biomarkers \[TIMP-2\]\*\[IGFBP-7\], released in response to tubular epithelial cell stress, have been reported to indicate the presence of acute renal injury (AKI) early on, before functional loss occurs (increased creatinine). This observational study aims to evaluate the renal resistance index and urinary biomarker variation in patients diagnosed with sepsis and to investigate their usefulness in the early detection of renal dysfunction that may develop after sepsis.
Trial Details
NCT Number NCT07472452
Lead Sponsor Ankara Etlik City Hospital
Conditions Acute Kidney Injury, Sepsis, Critical Illness, Renal Resistive Index
Enrollment 130 participants
Start Date 2026-03-30
Primary Completion 2026-06-30 (estimated)
Study Completion 2027-01-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-16