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Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms

StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 2 months later Aug 2026 → Nov 2026
See other at-risk trials from University of Kansas Medical Center

Record History

  1. Minor Primary and study completion pushed from Aug 2026 to Nov 2026 Eligibility criteria expanded, about 6 words · Site contact updated · Publications: details revised at 5 of 5 entries Show 3 more changesShow less
    • Eligibility criteria expanded, about 6 words
    • Site contact updated
    • Publications: details revised at 5 of 5 entries
  2. Notable Recruitment opened Primary completion pushed from Jun 2026 to Aug 2026 · Start date changed from estimate of Mar 2026 to Apr 29, 2026 · Site details revisedv2 Show 3 more changesShow less
    • Primary completion pushed from Jun 2026 to Aug 2026
    • Start date changed from estimate of Mar 2026 to Apr 29, 2026
    • Site details revised
  3. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Patellofemoral joint (PFJ) pain is a common, often chronic, aching pain behind or around the kneecap, frequently called "runner's knee". It occurs when the kneecap does not glide smoothly over the thigh bone, often due to muscle weakness or overuse. It makes sitting for long periods, climbing stairs, or kneeling painful. Symptomatic knee osteoarthritis (OA) is a common, long-term condition where the protective cartilage in the knee joint wears away, causing the bones to rub together, leading to daily pain and stiffness. In simple terms, it is a "wear-and-tear" disease of the entire joint that makes walking, climbing stairs, or bending the knee difficult. The PFJ is where the patella (kneecap) meets the femoral trochlea (front part of the lower thigh bone) at the front of the knee. Patellar tracking refers to the movement of the patella that begins to engage in the distal femoral trochlear groove (smooth, U-shaped groove at the bottom of the thigh bone). By doing this study, we hope to advance clinical knowledge of the PTJ features in a more natural position by using weight-bearing computed tomography (WBCT) images while the leg is straight and slightly bent. Determining links between specific knee symptoms and the PTJ structure on WBCT images could enable providers to effectively target the underlying causes and to develop targeted treatments.
Trial Details
NCT Number NCT07472088
Lead Sponsor University of Kansas Medical Center
Conditions Knee Osteoarthritis, Patellofemoral Pain (PFPS)
Enrollment 36 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov