Clinical Trial

Symptomatic and Systemic Atherosclerotic Plaque Activity in Patients With Peripheral Arterial Disease Using Novel Imaging

Name: Symptomatic and Systemic Atherosclerotic Plaque Activity in Patients With Peripheral Arterial Disease Using Novel Imaging — clinical trial record (NCT07472049)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: SISYPHUS

Recruiting

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Summary

The goal of this observational study is to characterise the relationships between inflammation, microcalcification and thrombus activity in atherosclerotic plaques in peripheral and systemic vascular territories in patients with symptomatic peripheral arterial disease.

Trial Details

NCT Number	NCT07472049
Lead Sponsor	University of Edinburgh Collaborators: NHS Lothian
Conditions	Peripheral Arterial Disease, Chronic Limb Threatening Ischemia
Enrollment	100 participants
Start Date	2025-07-31
Primary Completion	2028-07 (estimated)
Study Completion	2029-07 (estimated)
Updated on ClinicalTrials.gov	2026-03-16