The Mouth Matters in Mental Health Trial -2

This clinical trial will evaluate the effectiveness and cost-effectiveness of a link work intervention for supporting people with severe mental health difficulties to attend a routine dental appointment. There are two main outcomes, namely: i) attendance at a routine dental appointment; and ii) oral health quality of life. The main predictions are that: 1. The link work intervention plus treatment as usual will lead to greater likelihood of attendance at a routine dental appointment, compared with treatment as usual alone. 2. The link work intervention plus treatment as usual will lead to better oral health quality of life, compared with treatment as usual alone. 3. The link work intervention plus treatment as usual will be cost-effective compared with treatment as usual alone.

NCT Number	NCT07470437
Lead Sponsor	Lancashire and South Cumbria NHS Foundation Trust Collaborators: Greater Manchester Mental Health NHS Foundation Trust, Pennine Care NHS Foundation Trust, Northumberland, Tyne and Wear NHS Foundation Trust, South London and Maudsley NHS Foundation Trust, Lancaster University, University of Liverpool, University of Leeds, University of Manchester, King's College London
Conditions	Mental Health, Oral Health Care, Psychosis
Enrollment	480 participants
Start Date	2026-05-01
Primary Completion	2029-07-31 (estimated)
Study Completion	2029-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-07-27