Clinical Trial

A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors

Name: A Phase I Study of SY-9453 in Patients With Advanced Solid Tumors — clinical trial record (NCT07469982)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Recruiting Phase 1

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Summary

This is an open-label, single-arm, multicenter, dose-escalation and dose-expansion, phase I study to the safety, tolerability, pharmacokinetics, and preliminary efficacy of SY-9453 in patients with advanced solid tumors.

Protocol Amendment History 1 change

critical Recruitment opened 2026-04-28

Trial Details

NCT Number	NCT07469982
Lead Sponsor	Shouyao Holdings (Beijing) Co. LTD Collaborators: Shanghai East Hospital
Conditions	Advanced or Metastatic Solid Tumors With Homozygous MTAP Deletion
Enrollment	122 participants
Start Date	2026-03-12
Primary Completion	2027-02 (estimated)
Study Completion	2029-02 (estimated)
Updated on ClinicalTrials.gov	2026-04-27