Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer

This clinical trial tests the effect of focal radiation therapy, high dose rate-brachytherapy (HDR-BT), in treating patients with prostate cancer. Prostate cancer is the most diagnosed cancer in men and there are many treatments available, including surgery and radiation therapy. Although surgery and radiation therapy improve survival urinary and sexual function can be significantly affected and can be long lasting. HDR-BT, a type of focal radiation therapy also known as internal radiation therapy, uses radioactive material placed directly into or near a tumor to kill tumor cells. Giving HDR-BT may be effective in providing local control while reducing side effects in patients with prostate cancer.

NCT Number	NCT07468903
Lead Sponsor	Jonsson Comprehensive Cancer Center
Conditions	Prostate Adenocarcinoma, Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8, Stage II Prostate Cancer AJCC v8
Enrollment	45 participants
Start Date	2026-05-11
Primary Completion	2031-05-11 (estimated)
Study Completion	2032-05-11 (estimated)
Updated on ClinicalTrials.gov	2026-05-22