A Proof-of-concept Study of Ultrasound Stimulation of the Neck to Enhance Anti-shock Efficacy

The objective of this clinical study is to evaluate the initial efficacy and safety of LIPUS as an adjunct to standard therapy in patients with shock. The investigators will invite patients to participate in a proof-of-concept study investigating the efficacy of neck ultrasound stimulation to enhance anti-shock treatment, involving brief exposure to low-intensity pulsed ultrasound. This study examines whether LIPUS can enhance blood pressure in patients with shock, improve the efficacy of antihypotensive treatment, and reduce the dosage and duration of vasoactive drugs during active pharmacological therapy. By applying LIPUS as an adjunct to conventional treatment in clinical cases of shock, we aim to determine the clinical value of LIPUS and establish a theoretical foundation for developing innovative new therapies for shock.

NCT Number	NCT07467798
Lead Sponsor	Tao Liu Collaborators: Tianjin Medical University General Hospital, Xuanwu Hospital, Beijing
Conditions	Shock
Enrollment	30 participants
Start Date	2026-05
Primary Completion	2027-05 (estimated)
Study Completion	2027-11 (estimated)
Updated on ClinicalTrials.gov	2026-04-22