A Prospective Clinical Investigation of DMFI300 for Treating Nasolabial Folds

This is a prospective, randomized, controlled clinical investigation designed to evaluate the performance and safety of DMFI300 for the treatment of nasolabial folds. 30 adult participants will receive treatment with the investigational device and the comparator device using a split-face design. The study will assess wrinkle severity using validated aesthetic evaluation scales, as well as overall safety.

NCT Number	NCT07467239
Lead Sponsor	Samyang Biopharmaceuticals Corporation
Conditions	Nasolabial Folds, Wrinkles
Enrollment	30 participants
Start Date	2026-03-02
Primary Completion	2027-03-31 (estimated)
Study Completion	2027-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-12