Clinical Trial

Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis

Study acronym: MINST vs NSPT
Recruiting
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Summary
This multicenter, single-masked randomized controlled clinical trial evaluates the effectiveness of minimally-invasive non-surgical therapy (MINST) compared with standard non-surgical peri-implant therapy (NSPT) in patients diagnosed with peri-implantitis. The study investigates clinical outcomes, radiographic bone levels, patient-reported outcomes, and treatment time over 12 months.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-03-08.
Trial Details
NCT Number NCT07466966
Lead Sponsor St. Anne's University Hospital Brno, Czech Republic
Collaborators: King's College London
Conditions Peri-implantitis, Periodontitis, Non-surgical Periodontal Therapy
Enrollment 106 participants
Start Date 2026-01-01
Primary Completion 2028-01 (estimated)
Study Completion 2028-04 (estimated)
Updated on ClinicalTrials.gov 2026-03-13