Clinical Trial

Dento-skeletal Effects of Quadhelix Versus Mini-hyrax Expanders in Patients With Cleft Lip and Palate at the Mixed Dentition Stage: A Randomized Clinical Trial

Study acronym: RCT
Active, Not Recruiting
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Record status
This record was last updated March 12, 2026 (before its estimated April 2026 completion). Its status may not reflect the trial's current state.
Summary
Regarding expansion in cleft lip and palate patients, very few clinical trials were found after searching literature and fewer randomized trials. This means that no enough evidence in literature is tackling expansion in cleft lip and palate patients. To the best of our knowledge, this study will represent the first RCT to compare the dentoskeletal effects of mini-hyrax vs quadhelix. Since cleft cases usually need greater anterior than posterior expansion, both appliances are capable of anterior expansion. Nevertheless, no other study compared how much anterior expansion could be accomplished by either appliance.
Trial Details
NCT Number NCT07465939
Lead Sponsor Cairo University
Conditions Maxillary Expansion in Cleft Lip and Palate Patients, Dentoskeletal Effects After Expansion Using Two Different Expanders
Enrollment 24 participants
Start Date 2025-05-29
Primary Completion 2026-04 (estimated)
Study Completion 2026-05 (estimated)
Updated on ClinicalTrials.gov 2026-03-12