Clinical Trial

Effect of Fire-Needle Combined With Regular Acupuncture on Pregnancy Outcome in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization

Completed
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Summary
This study aims to evaluate whether fire-needle combined with regular acupuncture improves pregnancy outcomes in patients with recurrent implantation failure (RIF), compared to no or regular acupuncture. A retrospective cohort study was conducted at a university-affiliated hospital. One hundred RIF patients undergoing embryo transfer between July 2024 and June 2025 were assigned to three groups: a non-acupuncture group, a regular acupuncture group, and a fire needle combination group (receiving both fire needle and regular acupuncture). Key outcome measures, including the β-hCG positive rate, clinical pregnancy rate (CPR), and miscarriage rate (MR), were compared among the three groups.
Trial Details
NCT Number NCT07462754
Lead Sponsor Huazhong University of Science and Technology
Conditions Implantation Failure
Enrollment 100 participants
Start Date 2024-07-01
Primary Completion 2025-06-30 (estimated)
Study Completion 2025-10-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-10