Clinical Trial

Self-hangIng Patient and Hyperbaric Oxygen Therapy _ SIPHON Study

Study acronym: SIPHON
Not Yet Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
During an attempted hanging, patients present severe neurological distress that can lead to major neuropsychiatric sequelae. These sequelae are notably due to significant cerebral edema related to hanging. Hyperbaric Oxygen therapy is known to reduce cerebral edema and improve cerebral perfusion. The main objective of the study is to evaluate in patients who have attempted hanging without presenting cardio-respiratory arrest, the effect of one Hyperbaric Oxygen therapy session in addition to standard intensive care management on a potential reduction in short-term neurological sequelae. Patients will benefit from either standard management or standard management associated with one Hyperbaric Oxygen therapy session
Protocol Amendment History 2 changes
notable Primary completion pushed: 2028-09 -> 2028-12 2026-05-07
minor Completion pushed: 2028-09 -> 2028-12 2026-05-07
Trial Details
NCT Number NCT07461272
Lead Sponsor University Hospital, Lille
Conditions Suicide
Enrollment 50 participants
Start Date 2026-06
Primary Completion 2028-12 (estimated)
Study Completion 2028-12 (estimated)
Updated on ClinicalTrials.gov 2026-05-22