Mesenteric Ischemia Markers Study

Vascular bowel disease remains a socially significant and potentially fatal condition (if it develops into AMI), primarily due to delayed diagnosis. Blood biomarkers are theoretically ideal for early risk stratification (like troponins in myocardial infarction). However, the existing evidence base is characterized by low quality and high heterogeneity, which hinders their use in clinical practice. Therefore, there is an urgent and unmet clinical need for high-quality, methodologically rigorous research to validate biomarkers in MI. A current study (MESMARK) is to be undertaken to identify combinations of biomarkers that can reliably identify mesenteric ischemia (MI) and distinguish between non-transmural and transmural clinical relevant ischemia.

NCT Number	NCT07460700
Lead Sponsor	Belarusian State Medical University
Conditions	Mesenteric Vascular Disease
Enrollment	120 participants
Start Date	2025-12-22
Primary Completion	2026-08-12 (estimated)
Study Completion	2026-12-12 (estimated)
Updated on ClinicalTrials.gov	2026-03-10