Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy

Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence comparing anesthetic strategies in ankle arthroscopy is limited. This multicenter randomized trial compares total intravenous anesthesia with propofol plus peripheral nerve block (PNB), general anesthesia plus PNB, and spinal anesthesia, with PACU-I recovery time as the primary outcome. Secondary outcomes include postoperative pain, opioid consumption, hospital length of stay, adverse events, recovery quality, satisfaction, limb weakness, and intraoperative hemodynamics.

NCT Number	NCT07460310
Lead Sponsor	Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions	Ankle Sprain, Ankle (Ligaments); Instability (Old Injury), Pain Management, ERAS, Ankle Arthroscopy
Enrollment	200 participants
Start Date	2026-03-01
Primary Completion	2026-11-01 (estimated)
Study Completion	2026-12-30 (estimated)
Updated on ClinicalTrials.gov	2026-03-10