Clinical Trial

TArget Trial Emulation Comparing Effectiveness of Tocilizumab vs Methotrexate In Corticosteroid-Treated GCA Patients

Name: TArget Trial Emulation Comparing Effectiveness of Tocilizumab vs Methotrexate In Corticosteroid-Treated GCA Patients — clinical trial record (NCT07459335)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: TACTIC-GCA

Completed

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Summary

This nationwide observational study emulates a target trial to compare the effect of tocilizumab versus methotrexate initiation on major adverse cardiovascular events (MACE) in patients with incident giant cell arteritis using the French National Health Data System (SNDS).

Trial Details

NCT Number	NCT07459335
Lead Sponsor	Groupe français d'étude des Maladies Inflammatoires de loeil
Conditions	Giant Cell Arteritis (GCA), Cardiovascular Diseases
Enrollment	1,667 participants
Start Date	2012-01-01
Primary Completion	2024-12-31 (estimated)
Study Completion	2024-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-09