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International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes

Study acronym: IMPEL
StatusNot Yet Recruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗

Record History

  1. Minor Study First Submitted
Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare systems. Evidence guiding optimal management remains limited and is largely derived from retrospective or single-center studies. IMPEL is an international, multicenter, time-bound, prospective observational cohort study designed to characterize real-world presentation, diagnostic pathways, operative and non-operative management, and short-term outcomes in adults presenting with mechanical large-bowel obstruction. By capturing standardized patient-level, radiologic, operative, and outcome data across diverse acute care settings, IMPEL aims to describe contemporary practice patterns, quantify variation in care, and identify factors associated with morbidity, mortality, and stoma-related outcomes.
Trial Details
NCT Number NCT07458867
Lead Sponsor European Society for Trauma and Emergency Surgery
Collaborators: Association of Surgeons of Great Britain and Ireland, European Society of Coloproctology, American Society of Colon and Rectal Surgeons, University of Pennsylvania
Conditions
(from sponsor)
Large Bowel Obstruction
Enrollment 500 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov