This randomized clinical trial aimed to compare the effects of Muscle Energy Techniques (METs) and Pilates exercises on pain and physical function in individuals with nonspecific low back pain. A total of 72 participants aged between 20 and 50 years were recruited from the University of Lahore Teaching Hospital, Lahore. Participants were randomly allocated into two groups: one group received Muscle Energy Techniques and the other group performed Pilates exercises. Each intervention session lasted 60 minutes, conducted four days per week for six weeks. Pain intensity was assessed using the Numeric Pain Rating Scale (NPRS), while physical function was evaluated using the Roland Morris Disability Questionnaire (RMDQ). The results were analyzed to determine the comparative effectiveness of the two interventions in reducing pain and improving functional ability among patients with nonspecific low back pain.