Clinical Trial

Neuromuscular Electrical Stimulation and Voluntary Muscle Contraction in Chronic Hemiplegic Stroke Patients

Active, Not Recruiting
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Summary
This single-blinded randomized controlled trial will be conducted at the Physical Therapy Department of the University of Lahore Teaching Hospital after approval from the Institute Research Ethics Board. Eligible participants will be recruited and randomly allocated into two groups by lottery method: Group A (control group) receiving conventional physical therapy, and Group B (experimental group) receiving neuromuscular electrical stimulation (NEMS) combined with voluntary muscle contraction. NEMS will be applied to the tibialis anterior, extensor hallucis longus, and extensor digitorum longus with standard stimulation parameters, while participants perform active dorsiflexion during stimulation. The assessor will remain blinded to group allocation. Outcome measures including spasticity (Modified Ashworth Scale), active range of motion (goniometer), and muscle strength (manual muscle testing) will be evaluated at baseline, 6 weeks, and 12 weeks.
Protocol Amendment History 4 changes
notable Primary completion pushed: 2026-04-30 -> 2026-08-30 2026-07-16
minor Completion pushed: 2026-04-30 -> 2026-08-30 2026-07-16
notable Primary completion pushed: 2026-03-20 -> 2026-04-30 2026-04-14
minor Completion pushed: 2026-03-30 -> 2026-04-30 2026-04-14
Trial Details
NCT Number NCT07458750
Lead Sponsor University of Lahore
Conditions Stroke
Enrollment 25 participants
Start Date 2025-02-10
Primary Completion 2026-08-30 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-15