Clinical Trial

The Effect of Epidural Anesthesia on Optic Nerve Sheath Diameter Measurements in Total Knee Prosthesis Surgery

Completed
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Summary
This study investigates the effects of epidural anesthesia on intracranial pressure (ICP) by using ultrasonographic optic nerve sheath diameter (ONSD) measurements as a non-invasive indicator. The study aims to determine if the volume of local anesthetic applied to the epidural space during total knee replacement surgery leads to transient increases in ONSD compared to spinal anesthesia. Participants are randomized into two groups to receive either epidural or spinal anesthesia, and their ONSD measurements are tracked before, during, and after the surgery.
Trial Details
NCT Number NCT07458321
Lead Sponsor Bursa City Hospital
Conditions Total Knee Replacement, Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Change
Enrollment 60 participants
Start Date 2023-12-06
Primary Completion 2024-01-06 (estimated)
Study Completion 2024-04-20 (estimated)
Updated on ClinicalTrials.gov 2026-03-09