Auditory Processing in DOC Patients

This prospective observational study investigates whether electroencephalography (EEG) can improve the differentiation between unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) in patients with severe acquired brain injury. The study further examines the association between EEG markers of auditory processing and long-term functional outcome at 12 months.

NCT Number	NCT07455682
Lead Sponsor	BDH-Klinik Hessisch Oldendorf
Conditions	Disorder of Consciousness, Unresponsive Wakefulness Syndrome, Minimally Conscious State
Enrollment	42 participants
Start Date	2026-04-15
Primary Completion	2027-11-30 (estimated)
Study Completion	2028-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-06