ART Trial: Transcatheter J-VALVE Versus Surgery for Aortic Regurgitation Therapy

The overall purpose of ART trial is to establish the Safety and Efficacy of the J-VALVE Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement in Patients with Grade≥3+ Native Aortic Regurgitation.

NCT Number	NCT07453407
Lead Sponsor	Second Affiliated Hospital, Zhejiang University, School of Medicine
Conditions	Aortic Regurgitation, Aortic Valve Insufficiency, Aortic Insufficiency
Enrollment	1,250 participants
Start Date	2026-03-05
Primary Completion	2029-03 (estimated)
Study Completion	2038-03 (estimated)
Updated on ClinicalTrials.gov	2026-08-12