Treatment Outcome and Patient-reported Outcomes in Patient Undergoing Non-surgical Root Canal Treatment With Different Irrigation Protocols

This study aims to evaluate and compare the clinical and patient-reported outcomes of passive ultrasonic irrigation (PUI) and laser-activated irrigation (LAI) versus conventional syringe irrigation in adult patients undergoing non-surgical root canal treatment on mature permanent teeth, and to identify the key factors that influence these outcomes.

NCT Number	NCT07453134
Lead Sponsor	Chulalongkorn University
Conditions	Root Canal Treatment, Irrigation Activation, Oral Health Quality of Life (OHQoL) Was Assessed, Post Operative Pain After Root Canal Therapy
Enrollment	90 participants
Start Date	2025-11-07
Primary Completion	2027-11-06 (estimated)
Study Completion	2028-04-30 (estimated)
Updated on ClinicalTrials.gov	2026-03-05