Clinical Trial

Small Study Comparing Two Pain Medicines in Teenagers for Pain Control After Scoliosis Corrective Surgery.

Study acronym: KetaMorph
Not Yet Recruiting
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Summary
The goal of this clinical trial is to evaluate whether adding low-dose ketamine to PCA morphine reduces opioid requirements after posterior spinal fusion surgery in adolescent idiopathic scoliosis patients. Selected patients aged 10-18 years undergoing elective AIS surgery at University Malaya Medical Centre will be randomised to ketamine-morphine or morphine-only PCA. The primary outcome is cumulative morphine consumption at 48 hours, with secondary outcomes including pain scores, opioid-related adverse effects, time to ambulation, and patient satisfaction. This study aligns with national priorities for safe opioid stewardship and enhanced peri-operative care in Malaysia.
Trial Details
NCT Number NCT07452705
Lead Sponsor University of Malaya
Conditions Adolescent Idiopathic Scoliosis (AIS)
Enrollment 114 participants
Start Date 2026-02-02
Primary Completion 2027-07-01 (estimated)
Study Completion 2028-01-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-05