Comparison of Dry Needling and Two Botulinum Toxins for Bruxism

1. Aim: The aim of this study is to prospectively compare the clinical efficacy of Dry Needling (DN), Nabota (PrabotulinumtoxinA), and Dysport (AbobotulinumtoxinA) treatments on the thickness of masseter and anterior temporal muscles and pain intensity (VAS) in patients diagnosed with chronic bruxism. 2. Material and Method: This randomized, prospective, and single-blind clinical study will be conducted on 60 patients diagnosed with bruxism. Patients will be divided into three groups: Dry Needling (n=20), Nabota (n=20), and Dysport (n=20). Pain levels will be assessed using the Visual Analog Scale (VAS) at baseline, 1st month, and 3rd month. Muscle thicknesses will be measured using ultrasonography (USG) at baseline and 3rd month. Data distribution will be analyzed using the Kolmogorov-Smirnov test; intergroup comparisons will be performed using ANOVA and Post-hoc Duncan tests. 3. Results:The results will be analyzed following the completion of the 3-month follow-up period

NCT Number	NCT07452510
Lead Sponsor	Recep Tayyip Erdogan University
Conditions	Bruxism, Sleep Bruxism, Adult, Awake Bruxism, Masseter Muscle Hypertrophy, Temporomandibular Disorders
Enrollment	72 participants
Start Date	2026-01-09
Primary Completion	2026-04-08 (estimated)
Study Completion	2026-04-08 (estimated)
Updated on ClinicalTrials.gov	2026-05-20