Clinical Trial

Comparison of Vicryl Versus Prolene for Midline Rectus Sheath Closure After Elective Laparotomy

Completed
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Summary
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy. Proper closure of the abdominal wall is important to reduce complications such as wound dehiscence and surgical site infection. Adult patients undergoing elective midline laparotomy were randomly assigned to rectus sheath closure using either Prolene or Vicryl sutures. All patients received the same standardized surgical technique and postoperative care. Participants were followed for 30 days after surgery to assess wound healing, wound dehiscence, surgical site infection, and length of hospital stay. The study aimed to determine which suture material is associated with fewer postoperative wound complications.
Trial Details
NCT Number NCT07451990
Lead Sponsor Hayatabad Medical Complex
Conditions Laparotomy Closure After Abdominal Surgery, Suture Materials, Complications Wounds
Enrollment 152 participants
Start Date 2024-04-01
Primary Completion 2025-10-30 (estimated)
Study Completion 2025-11-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-05