Clinical Trial

Comprehensive Multi-omics Characterization and Implications of Non-Pharmaceutical Dental Hygiene Product in a Randomized Controlled Large Population Study.

Completed
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Summary
The goals of this clinical study are: 1. Survey approximately 600 persons between the ages of 18-80 regarding their medical history \& oral hygiene habits, diet \& exercise habits, and emotional \& physical stressors to understand the barriers this population may face in achieving or maintaining good oral care and whole body health. 2. Compare the survey results with the organic molecule data collected by oral swabs from each subject at three different time points over the course of their 60 day study participation to better understand how behaviors and medical history relate to oral and whole body health. 3. Assess the effectiveness of two marketed oral hygiene study products vs a control on oral microbiome--such as bacteria, fungi, viruses that live naturally in our body-as well as its impact on the oral microbiome of each subject. The study products used in this study are 1 marketed oral lozenge, 1 marketed water additive.
Trial Details
NCT Number NCT07451782
Lead Sponsor Delta Dental of Minnesota Foundation
Collaborators: Comprehensive Research Group, Primal Therapies Inc., Clinical Microbiomics
Conditions Basic Science, Intervention Studies, Biomarker Discovery
Enrollment 595 participants
Start Date 2024-04-30
Primary Completion 2024-07-11 (estimated)
Study Completion 2025-07-23 (estimated)
Updated on ClinicalTrials.gov 2026-03-05