Clinical Trial

Sensory Substitution and Brain Plasticity Following Vision Loss

Study acronym: SenSubMRI
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Summary
The goal of this clinical investigation is to learn how the brain responds when visual information is converted into patterns of sound or touch in blind and sighted participants. The main questions it aims to answer are: * Does converting visual information into sound or touch patterns change visual performance in the blind or blindfolded? * How does the brain adapt to different kinds of sensory information? Researchers will use brain imaging and simple performance tasks to see how people process and learn from this type of converted sensory input. The investigators will compare how individuals with and without long-term vision loss respond to these signals. Participants will: * Learn to use technologies to assist in visual information conversion into sound or touch patterns every day for 5 weeks; * Visit the brain imaging center 3 times for brain scans and behavioral tests.
Trial Details
NCT Number NCT07450677
Lead Sponsor Stanford University
Collaborators: National Eye Institute (NEI)
Conditions Blindness
Enrollment 200 participants
Start Date 2026-06-01
Primary Completion 2030-08-31 (estimated)
Study Completion 2030-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-05