Clinical Trial

Effect of Preoperative Long-Acting Corticosteroids on Pain, Swelling, and Trismus After Impacted Lower Third Molar Surgery

Active, Not Recruiting
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Record status
This record was last updated March 5, 2026 (before its estimated April 4, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study evaluated whether giving a single dose of long-acting corticosteroids before wisdom tooth surgery reduces pain, facial swelling, and limited jaw opening (trismus) after surgery. Adult patients aged 18-35 undergoing impacted lower wisdom tooth removal were randomly assigned to receive either 8 mg dexamethasone or a placebo before surgery. Pain, swelling, and jaw mobility were measured at several time points after surgery. The study aimed to determine if preoperative corticosteroids improve recovery and reduce discomfort following surgery.
Trial Details
NCT Number NCT07450638
Lead Sponsor Al Salam University
Conditions Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Facial Swelling
Enrollment 60 participants
Start Date 2026-01-04
Primary Completion 2026-04-04 (estimated)
Study Completion 2026-04-15 (estimated)
Updated on ClinicalTrials.gov 2026-03-05