Clinical Trial

The Practicality and Utility of Measured vs Estimated GFR in adCKD

Not Yet Recruiting
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Summary
The goal of this observational study is to assess if new ways of measuring kidney function can better predict when individuals will become symptomatic due to kidney failure, and whether residual kidney function can be accurately measured in those already on dialysis. The main questions the study is trying to answer is whether measuring kidney function by clearance of iohexol is comparable to the current standard of care methods. In addition to routine care, participants will: * undergo a brief clinical assessment * be given an injection of iohexol and asked to perform 4 finger prick blood tests over 24 hours, recording the time of each sample. Samples will be returned in person or posted back * be asked to complete a questionnaire on their experience
Trial Details
NCT Number NCT07450534
Lead Sponsor Manchester University NHS Foundation Trust
Conditions Chronic Kidney Disease (Stages 4 and 5), Chronic Kidney Disease 5D
Enrollment 150 participants
Start Date 2026-02
Primary Completion 2026-09 (estimated)
Study Completion 2027-02 (estimated)
Updated on ClinicalTrials.gov 2026-03-04