Biochemical Response and Clinical Outcomes in Patients With PBC

This study is a bidirectional cohort study. The investigators conduct a bidirectional cohort study utilizing a database in mainland China, continuously collecting demographics, clinical symptoms, and biochemical characteristics of diagnosed PBC patients. The study aims to analyze the association between varying post-treatment alkaline phosphatase (AKP) levels and complication-free survival rates, with the objective to develop and validate a predictive survival model.

NCT Number	NCT07449793
Lead Sponsor	RenJi Hospital
Conditions	Primary Biliary Cholangitis (PBC), Primary Biliary Cholangitis
Enrollment	3,000 participants
Start Date	2026-02-01
Primary Completion	2027-07-31 (estimated)
Study Completion	2028-01-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-04