Effects of Short-Term Resistance Training on Diaphragm Thickness, Hepatic Fat Density, and Quality of Life in Healthy Older Men

This randomized controlled trial investigated the effects of a four-week moderate-intensity resistance training program on diaphragm thickness, hepatic fat density, and health-related quality of life in healthy community-dwelling older men aged 60-75 years. Thirty participants were randomly assigned to a resistance training group or control group. Diaphragm thickness and hepatic attenuation were assessed using non-contrast computed tomography, and quality of life was evaluated using the SF-12 questionnaire. The primary outcome was change in diaphragm thickness. Secondary exploratory outcomes included hepatic fat density and SF-12 physical and mental health scores.

NCT Number	NCT07449767
Lead Sponsor	Gümüşhane Universıty
Conditions	Older Men, Quality of Life, Fatty Liver, Resistance Training, Aging
Enrollment	30 participants
Start Date	2025-06-10
Primary Completion	2025-07-25 (estimated)
Study Completion	2025-08-10 (estimated)
Updated on ClinicalTrials.gov	2026-03-05