Clinical Trial

The Influence of Laser Crossectomy With Different Wavelengths on Varicose Vein Progression

Study acronym: LACROSS-VVP
Recruiting
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Summary
Technically successful laser crossectomy will reduce the risk of reflux recurrence at the sapheno-femoral junction without increasing the risk of endovenous heat-induced thrombosis, which may positively impact the likelihood of ultrasound- or clinical-recurrence of varicose veins. Similar technical efficacy is expected for laser crossectomy at 1940 nm and 1470 nm. A possible advantage of the 1940 nm wavelength in terms of postoperative pain intensity and the risk of adverse events cannot be ruled out.
Trial Details
NCT Number NCT07449728
Lead Sponsor Pirogov Russian National Research Medical University
Conditions Varicose Veins, Chronic Venous Insufficiency
Enrollment 400 participants
Start Date 2026-01-20
Primary Completion 2028-01-20 (estimated)
Study Completion 2029-01-20 (estimated)
Updated on ClinicalTrials.gov 2026-03-04