Clinical Trial

SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty

Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated May 22, 2026 (before its estimated May 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.
Protocol Amendment History 1 change
critical Recruitment opened 2026-05-23
Trial Details
NCT Number NCT07449442
Lead Sponsor Poznan University of Medical Sciences
Conditions Knee Osteoarthritis
Enrollment 60 participants
Start Date 2026-03-01
Primary Completion 2026-05-31 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-22