Clinical Trial

SII Levels Following PENG Block in Hip Arthroplasty

Recruiting
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Summary
This randomized controlled trial evaluates the effect of ultrasound-guided Pericapsular Nerve Group (PENG) block on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether PENG block attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.
Protocol Amendment History 3 changes
critical Recruitment opened 2026-07-02
notable Primary completion pushed: 2026-05-01 -> 2026-09-01 2026-07-02
minor Completion pushed: 2026-06-30 -> 2026-09-30 2026-07-02
Trial Details
NCT Number NCT07449403
Lead Sponsor Poznan University of Medical Sciences
Conditions Hip Osteoarthritis
Enrollment 60 participants
Start Date 2026-03-01
Primary Completion 2026-09-01 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-01