Rct Assessing Pregnancy - Piroxicam for Ec With Levonorgestrel

This randomized controlled trial will test oral levonorgestrel + piroxicam vs. levonorgestrel + placebo for emergency contraception in a representative U.S. population that has higher pregnancy risk than in the prior study because of higher weights, different intercourse patterns, and different clinic accessibility. Data from this project will inform clinical practice in the U.S. and beyond for those desiring the most effective method of emergency contraception pills.

NCT Number	NCT07449299
Lead Sponsor	University of Utah
Conditions	Emergency Contraception, Contraception, COX-2 Inhibitor
Enrollment	1,458 participants
Start Date	2027-03
Primary Completion	2031-06 (estimated)
Study Completion	2031-11 (estimated)
Updated on ClinicalTrials.gov	2026-03-04