Clinical Trial

Cognitive-Frailty Gait Biomechanics for Early Dementia Detection

Study acronym: gait dementia
Not Yet Recruiting
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Summary
The purpose of this study is to better understand how physical characteristics, walking patterns, and a blood-based brain health marker differ between older adults with dementia and healthy older adults. Dementia is often associated with changes in physical health and movement, but these changes are not fully understood. This study asks whether people with dementia show differences in body composition, walking ability, and levels of brain-derived neurotrophic factor (BDNF), a protein involved in brain function, compared with individuals without dementia. To answer this question, participants will complete a single assessment session that includes basic physical measurements, an assessment of walking while moving at a comfortable pace, and a small blood sample collection. The information collected will be used to compare the two groups and explore possible relationships between physical function, walking patterns, and BDNF levels.
Trial Details
NCT Number NCT07448909
Lead Sponsor Universiti Sains Malaysia
Conditions Mild Cognitive Impairment (MCI)
Enrollment 60 participants
Start Date 2026-02-01
Primary Completion 2028-12-31 (estimated)
Study Completion 2029-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-04