Clinical Trial

Real-life Ecological Momentary Assessment of Lived Burden in Hereditary AngioEdema

Study acronym: REAL-HAE
Recruiting
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Summary
The aim of this study is to conduct an in-depth analysis of the Burden of Disease (BoD) perceived by patients with Hereditary Angioedema (HAE), through daily prospective observations based on Ecological Momentary Assessment (EMA) via digital surveys and standardised questionnaires. Participants will answer online survey questions about their perceived burden of disease for 8 consecutive weeks. The main hypothesis is that daily prospective observation (EMA) will reveal a higher and more fluctuating burden of disease compared to traditional retrospective scales, providing a more accurate representation of the impact of HAE on patients' daily lives.
Trial Details
NCT Number NCT07448181
Lead Sponsor Istituti Clinici Scientifici Maugeri SpA
Conditions Hereditary Angioedema With C1 Esterase Inhibitor Deficiency, Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2
Enrollment 30 participants
Start Date 2026-02-23
Primary Completion 2027-02-28 (estimated)
Study Completion 2027-02-28 (estimated)
Updated on ClinicalTrials.gov 2026-03-04