Real-World Case Registry Study on Obesity

Obesity is a major risk factor for cardiovascular disease, diabetes, cancer, and other chronic conditions. Due to its complex etiology and frequent comorbidities, effective obesity management requires comprehensive and individualized approaches. This study is a multicenter, prospective, real-world registry designed to evaluate integrated traditional Chinese medicine (TCM) and Western medicine interventions for obesity. The study will enroll at least 10,000 individuals with obesity from urban and rural populations. Multimodal data, including electronic medical records, laboratory test results, imaging data, and lifestyle information, will be collected. The effectiveness of integrated TCM and Western medicine interventions will be assessed across different age groups, disease stages, and obesity-related constitution types. In addition, disease progression patterns and key prevention and treatment points will be explored. Health economic analyses will be conducted to evaluate the cost-effectiveness of different obesity management strategies, providing real-world evidence to support public health policy and the optimization of integrated obesity prevention and management approaches.

NCT Number	NCT07448090
Lead Sponsor	Hubei Hospital of Traditional Chinese Medicine Collaborators: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Heilongjiang Quanle Pharmaceutical Co., Ltd., Huazhong University of Science and Technology
Conditions	Obesity & Overweight, Obesity (Disorder)
Enrollment	10,000 participants
Start Date	2024-08-31
Primary Completion	2028-07-31 (estimated)
Study Completion	2028-07-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-12