Clinical Trial

Prospective Analysis of Arteriovenous Access (AVA) Use in Continuous Renal Replacement Therapy: A Feasibility Project

Study acronym: CRRT
Not Yet Recruiting
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Summary
This study will test whether patients who already have a permanent dialysis access (an arteriovenous fistula or graft) can safely use that access for continuous dialysis (CRRT) while they are critically ill in the intensive care unit, instead of requiring a temporary central venous catheter. About 50 patients will participate. Researchers will monitor how well the access works, whether any complications occur, and whether there are differences between fistulas and grafts. The goal is to determine whether using a patient's existing dialysis access is a safe and practical option that could reduce the need for temporary catheters and their associated risks, such as infection and bleeding.
Protocol Amendment History 4 changes
critical Phase changed: not specified -> not applicable 2026-07-07
critical Primary endpoint(s) modified 2026-07-07
notable Primary completion pushed: 2026-06 -> 2027-09-30 2026-07-07
minor Completion pushed: 2026-09 -> 2027-12-31 2026-07-07
Trial Details
NCT Number NCT07447128
Lead Sponsor East Carolina University
Conditions Continuous Renal Replacement Therapy (CRRT), End Stage Kidney Disease (ESRD)
Enrollment 50 participants
Start Date 2026-07-27
Primary Completion 2027-09-30 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-06