Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07447063 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

The Impact of Dietary Salt on the Severity of Eczema

Study acronym: iDOSE
StatusRecruiting
PhasePhase 4
Started2026-08-10
View on ClinicalTrials.gov ↗

Amendment history

2026-09-08
notable
Study Status, Contacts/Locations v3
Recruitment opened
Start dateestimated 2026-06-22→confirmed 2026-08-10
Study sitesdetails revised at 2 of 2 sites
2026-06-05
minor
Study Status v2
Start date2026-03-06→2026-06-22
2026-03-13
minor
Study Status, Outcome Measures v1
Secondary endpoints6 entries, revised
Atopic dermatitis severity andmeasured persistenceby POEM score Atopic dermatitis severitycontrol measured by mean RECAP score AtopicParticipant-reported dermatitisitch severityscore AtopicSkin-related dermatitisquality severityof life score
2026-02-25
minor
Original filing
The goal of this clinical trial is to evaluate the feasibility of low-sodium diet to improve eczema severity. The main questions it aims to answer are: * Does a low-sodium diet improve eczema severity? * How does a low-sodium diet impact skin sodium concentration? * Is skin sodium concentration associated with eczema severity? Researchers will ask all participant to follow a low-sodium diet, then compare sodium tablets to a placebo (a look-alike substance that contains no drug) to specifically examine the impact of altering sodium intake. Participants will: * Follow a low-salt diet for the duration of the 24-week study * Take sodium chloride tablets every day for 5 weeks followed by a placebo every day for 5 weeks after a 2-week washout period, or vice versa * Complete up to 4 virtual check-in visits * Visit the clinic 4 times to answer questionnaires, provide bio samples, complete dietary recalls, and undergo non-contrast sodium MRI
Trial Details
NCT Number NCT07447063
Lead Sponsor University of California, San Francisco
Collaborators: United States Department of Defense
Conditions Eczema, Atopic Dermatitis
Enrollment 40 participants
Start Date 2026-08-10
Primary Completion 2028-03-05 (estimated)
Study Completion 2028-05-05 (estimated)
Updated on ClinicalTrials.gov 2026-09-10