Clinical Trial

Minimum Effective Volume of Bupivacaine for Serratus Posterior Superior Intercostal Plane Block in Video-Assisted Thoracoscopic Surgery

Study acronym: SPSIP-EV50
Recruiting
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Summary
This study aims to determine the minimum effective volume of bupivacaine required for the serratus posterior superior intercostal plane (SPSIP) block in patients undergoing video-assisted thoracoscopic surgery (VATS). The SPSIP block is an ultrasound-guided regional anesthesia technique used to provide postoperative pain relief after thoracic surgery. Using a stepwise dose-adjustment method, the volume of local anesthetic will be increased or decreased based on the effectiveness of the block in each patient. The main outcome of the study is to identify the volume that provides effective pain control in 50% of patients. The results may help optimize pain management while minimizing drug exposure.
Protocol Amendment History 2 changes
notable Primary completion moved earlier: 2026-07-15 -> 2026-05-11 2026-05-13
critical Recruitment opened 2026-04-01
Trial Details
NCT Number NCT07446959
Lead Sponsor Bursa City Hospital
Collaborators: Ulusoy, Emre, M.D.
Conditions Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS)
Enrollment 27 participants
Start Date 2026-03-15
Primary Completion 2026-05-11 (estimated)
Study Completion 2026-07-15 (estimated)
Updated on ClinicalTrials.gov 2026-05-12