Clinical Trial

TIS for Improving Cognitive Impairment Associated With Schizophrenia

Recruiting
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Record status
This record was last updated July 17, 2026 (before its estimated August 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study aims to evaluate the efficacy and safety of TIS targeting the hippocampus in ameliorating cognitive impairment associated with schizophrenia (CIAS). Participants will receive TIS twice a day for 2 weeks. Their clinical data, including the baseline clinical symptom scale score, cognitive function, and MRI data, will be collected at baseline and at the end of the 2-week intervention.
Protocol Amendment History 3 changes
critical Recruitment opened 2026-07-19
notable Primary completion pushed: 2026-05-01 -> 2026-08-01 2026-07-19
minor Completion pushed: 2026-05-15 -> 2026-08-15 2026-07-19
Trial Details
NCT Number NCT07446478
Lead Sponsor Central South University
Conditions Cognitive Impairment Associated With Schizophrenia (CIAS)
Enrollment 10 participants
Start Date 2026-06-24
Primary Completion 2026-08-01 (estimated)
Study Completion 2026-08-15 (estimated)
Updated on ClinicalTrials.gov 2026-07-17