TETANUS Antibody Detection in Saliva Study

This study aims to design, develop and optimise a non-invasive, saliva sample-based point-of-care lateral flow test for use in low and middle income settings that can return a qualitative result on whether an individual has or has not immunity to tetanus within 10-15mins. If successful, this approach would not require blood sampling or laboratory facilities, empower personalised decision making on vaccine needs and support the development of population level data-driven public health policies.

NCT Number	NCT07446166
Lead Sponsor	University of Birmingham Collaborators: Rwanda Biomedical Centre, Center for Family Health Research/Projet San Francisco
Conditions	Tetanus
Enrollment	390 participants
Start Date	2026-02-01
Primary Completion	2026-11-01 (estimated)
Study Completion	2028-02-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-03