Clinical Trial

Muévete conCiencia: Exercise and Mind-Body Program for University Students

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Summary
The goal of this clinical trial is to evaluate whether different physical exercise and mind-body interventions can improve executive functions and reduce stress in first-year university students. The study focuses on healthy undergraduate students, men and women, aged approximately 18-25 years, enrolled in health-related programs at a Chilean university. The main questions it aims to answer are: Do high-intensity dual-task physical exercise interventions improve executive functions (working memory, inhibitory control, and cognitive flexibility) and reduce stress in university students? Do mind-body exercise interventions (Tai Chi) reduce stress levels, measured through self-report and psychobiological biomarkers (cortisol)? Are there differential effects between high-intensity dual-task exercise, low-to-moderate intensity mind-body exercise, and cognitive training on executive functioning and stress-related outcomes? Researchers will compare: * high-intensity dual-task exercise group, * low-to-moderate intensity mind-body exercise group (Tai Chi), and * cognitive training group, To determine whether physically integrated motor-cognitive training produces greater improvements in executive functions and stress biomarkers than mind-body exercise or cognitive stimulation alone. Participants will: Complete baseline pre-intervention and post-intervention assessments, Neuropsychological tests of executive functions (working memory, inhibitory control, cognitive flexibility), Self-reported academic stress questionnaires, Psychobiological measures of stress (hair cortisol, salivary cortisol), Physical activity, anthropometric, and sociodemographic assessments. Participate for 12 weeks (22 sessions, twice per week) in one of the following interventions: High-intensity dual-task physical exercise, combining aerobic, strength, and motor-cognitive tasks; Low-to-moderate intensity mind-body exercise (Tai Chi) emphasizing mindful movement, balance, breathing, and attentional control; Cognitive training sessions using a structured digital program. All sessions will be conducted in supervised, controlled settings by trained professionals, following standardized protocols to ensure safety, consistency, and adherence.
Protocol Amendment History 3 changes
notable Enrollment increased: 120 -> 297 participants 2026-07-25
notable Primary completion pushed: 2026-03-31 -> 2026-09-30 2026-07-25
minor Completion pushed: 2026-12-30 -> 2027-04-30 2026-07-25
Trial Details
NCT Number NCT07443904
Lead Sponsor Universidad San Sebastián
Collaborators: Agencia Nacional de Investigación y Desarrollo
Conditions Healthy, Healthy Adult Participants
Enrollment 297 participants
Start Date 2026-08
Primary Completion 2026-09-30 (estimated)
Study Completion 2027-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-24