Prospective IR-led Sedation Feasibility

This study wants to see if some interventional radiology (IR) procedures can be done without using general anesthesia. General anesthesia needs a lot of staff and equipment. It can also cause side effects. There are not enough anesthesia providers, which makes it harder to use for every procedure. The researchers will test deep sedation with ketamine instead. They will start with 20 patients. If it works well and is safe, they may include up to 40 patients. Patients will be asked to join the study before their procedure. The anesthesia team will be told ahead of time and will be ready to help if needed. The IR team will give the deep sedation and follow all safety rules. The main goal is to finish the procedure without stopping early or switching to general anesthesia. The study will call this successful if fewer than 10% of cases fail. The researchers will also look at patient pain, patient satisfaction, any side effects, and how long recovery takes.

NCT Number	NCT07443254
Lead Sponsor	CAMC Health System
Conditions	Anesthesia, Sedation and Analgesia, Interventional Radiology
Enrollment	40 participants
Start Date	2026-03-02
Primary Completion	2027-04-03 (estimated)
Study Completion	2027-04-03 (estimated)
Updated on ClinicalTrials.gov	2026-03-09