Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07442552 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Perioperative Sepsis. An Epigenetic Perspective

Study acronym: PESE
StatusRecruiting
PhaseNot specified
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated March 2, 2026 (before its estimated March 30, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
This single-center, prospective, observational study evaluates the impact of perioperative sepsis on inflammatory response, coagulation abnormalities, cardiac dysfunction, and microRNA expression in adult patients undergoing major abdominal surgery. Forty patients are enrolled and classified into septic and non-septic groups according to international sepsis definitions based on SOFA score criteria. Clinical, biochemical, echocardiographic, and molecular parameters, including selected microRNAs, are assessed preoperatively and within the first 24 hours postoperatively. The study aims to characterize pathophysiological differences associated with perioperative sepsis and to explore the potential prognostic value of microRNAs as early biomarkers of postoperative sepsis.
Trial Details
NCT Number NCT07442552
Lead Sponsor Carol Davila University of Medicine and Pharmacy
Conditions
(from sponsor)		 Sepsis Abdominal
Related terms Intraabdominal Infections
Enrollment 40 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov